About
Amoxicillin is a widely used antibiotic in the penicillin group. It works by killing bacteria or preventing their growth.
It is commonly prescribed for infections such as:
- Ear, nose, and throat infections (e.g., sinusitis, tonsillitis)
- Respiratory tract infections (e.g., bronchitis, pneumonia)
- Urinary tract infections
- Skin and soft tissue infections
Amoxicillin can come in the form of:
- Capsules
- Tablets
- Oral suspension/liquid
- Powder for injection (rarely used outside hospitals)
How and When to Use It
Take amoxicillin exactly as prescribed by your doctor.
Dosage: Doses vary based on the infection and patient age. Adults commonly take 250–500 mg every 8 hours, or 500–875 mg every 12 hours.
For children, the dose is usually calculated based on body weight.
Take amoxicillin with or without food. Swallow capsules or tablets with water. Shake liquid preparations well before use.
Complete the full course even if you feel better. Stopping early can cause the infection to return and lead to antibiotic resistance.
Contraindications
Amoxicillin should not be taken if you have:
- Allergy to amoxicillin, penicillin, or any β-lactam antibiotic
- Severe kidney disease (dose adjustments may be needed)
- A history of cholestatic jaundice or liver dysfunction with previous amoxicillin use
Side Effects
Like all antibiotics, amoxicillin may cause side effects, although not everyone experiences them.
Common side effects:
- Nausea
- Vomiting
- Diarrhea
- Rash or mild allergic reactions
Rare but serious side effects:
- Severe allergic reactions (anaphylaxis)
- Clostridium difficile infection (severe diarrhea)
- Liver or kidney problems
Seek medical attention immediately if you experience swelling of face, lips, tongue, or difficulty breathing.
Pregnancy, Breastfeeding & Fertility
Amoxicillin is generally considered safe during pregnancy and breastfeeding. Small amounts pass into breast milk, but they are unlikely to harm the baby.
There is no evidence that amoxicillin affects fertility in men or women.
Interactions With Other Medications
Some medications can interact with amoxicillin:
- Allopurinol may increase the risk of skin rash
- Oral contraceptives may be slightly less effective
- Warfarin and other anticoagulants (may affect blood clotting)
- Other antibiotics (consult your doctor before combining)
Frequently Asked Questions
How does amoxicillin work?
Amoxicillin works by preventing bacteria from forming cell walls, causing them to break down and die, which stops the infection.
When will I feel better?
Most people start to feel better after a few days of treatment, but it’s important to complete the full course as prescribed.
What if I miss a dose?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one — never double up.
Can I take amoxicillin with food or milk?
Yes. Amoxicillin can be taken with or without food. Taking it with a meal or milk can help reduce stomach upset.
Are there any long-term side effects?
Long-term side effects are rare. Overuse can contribute to antibiotic resistance or mild gut imbalance.
Can I drink alcohol while taking it?
Amoxicillin does not interact directly with alcohol, but alcohol may delay recovery or worsen side effects like stomach upset.
Is it safe during pregnancy or breastfeeding?
Yes. Amoxicillin is generally safe during pregnancy and breastfeeding, but always confirm with your doctor before taking it.
Medical Disclaimer: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or changing any medication.
Last reviewed: June 2026
