About
Aripiprazole is an antipsychotic medicine used to treat conditions such as schizophrenia, bipolar disorder, and as an adjunct in major depressive disorder. It works by helping to restore the balance of certain natural chemicals (neurotransmitters) in the brain, particularly dopamine and serotonin.
Aripiprazole is commonly prescribed for:
- Treating schizophrenia in adults and adolescents
- Managing manic or mixed episodes in bipolar disorder
- Adjunct therapy in major depressive disorder
- Treating irritability associated with autism spectrum disorder
How and When to Use It
Take aripiprazole exactly as prescribed by your doctor.
Dosage: The dose depends on your condition, age, and response to treatment. Typical doses range from 2 mg to 30 mg per day, sometimes given as a single daily dose.
Swallow tablets or orally disintegrating tablets whole with water.
Aripiprazole can be taken with or without food.
Do not stop taking aripiprazole suddenly without consulting your doctor, as symptoms may worsen or withdrawal effects may occur.
Contraindications
Do not take aripiprazole if you have:
- An allergy to aripiprazole or any ingredients in the medicine
- A history of severe hypersensitivity reactions to other antipsychotics
- Conditions where sudden changes in blood pressure could be dangerous (consult your doctor)
Side Effects
Like all medicines, aripiprazole can cause side effects, although not everyone experiences them.
Common side effects:
- Insomnia or sleepiness
- Nausea or vomiting
- Headache
- Restlessness or agitation
- Weight gain
Serious side effects — seek medical attention immediately:
- Uncontrolled movements (tremors, stiff muscles, twitching)
- Severe dizziness or fainting
- Signs of infection (fever, sore throat)
- Unusual thoughts of self-harm or suicidal ideation
Contact your doctor immediately if you experience any serious reactions or sudden changes in mood or behavior.
Pregnancy, Breastfeeding & Fertility
Aripiprazole should only be used during pregnancy if clearly needed. Discuss risks and benefits with your doctor.
It is not recommended while breastfeeding without medical supervision.
There is no clear evidence that aripiprazole affects fertility in men or women.
Interactions With Other Medications
Some medicines can affect how aripiprazole works or increase side effects. Inform your doctor if you take:
- Other antipsychotics or mood stabilizers
- Medications that affect liver enzymes (e.g., certain antibiotics, antifungals, or anticonvulsants)
- Medications that prolong the QT interval (e.g., some heart rhythm drugs)
- Herbal supplements, especially St John’s wort
Frequently Asked Questions
How long does aripiprazole take to work?
It may take several weeks to notice full benefits, especially for mood or psychotic symptoms. Some improvement may occur within 1-2 weeks.
Can I take aripiprazole for sleep problems?
Aripiprazole is not primarily used for sleep issues. Discuss alternatives with your doctor.
Will aripiprazole cause weight gain?
Some people may experience weight gain. Lifestyle measures like diet and exercise may help manage this.
Can I drink alcohol while taking aripiprazole?
Alcohol may worsen drowsiness, dizziness, or other side effects. Avoid or limit alcohol while taking aripiprazole.
Is it safe to drive while taking aripiprazole?
Do not drive until you know how aripiprazole affects you, as it may cause drowsiness or slow reaction times.
What should I do if I miss a dose?
Take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Can I stop taking aripiprazole suddenly?
Do not stop suddenly. Your doctor will guide you to gradually reduce the dose to avoid withdrawal or symptom relapse.
Medical Disclaimer: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or changing any medication.
Last reviewed: June 2026
