About
Atorvastatin is a medicine used to lower cholesterol and reduce the risk of heart disease. It belongs to a class of drugs called statins. It works by reducing the amount of cholesterol made by your liver, lowering levels of "bad" LDL cholesterol and triglycerides, and raising "good" HDL cholesterol.
Atorvastatin is commonly prescribed for:
- High cholesterol (hypercholesterolemia)
- Prevention of heart attacks or strokes in people at risk
- Management of atherosclerosis (hardening of the arteries)
- Reducing cardiovascular risk in people with diabetes or other risk factors
Atorvastatin is available in:
- Tablets (10 mg, 20 mg, 40 mg, 80 mg)
How and When to Use It
Take atorvastatin exactly as prescribed by your doctor.
Dosage: Usually taken once daily, at any time of day, with or without food. Your doctor will determine the dose based on your cholesterol levels and risk factors.
Swallow tablets with water. Do not crush or chew extended-release tablets.
Continue taking atorvastatin even if you feel well — high cholesterol usually has no symptoms. Do not stop without consulting your doctor.
Contraindications
Do not take atorvastatin if you have:
- Allergy to atorvastatin or other statins
- Active liver disease or unexplained persistent liver enzyme elevations
- Pregnancy or breastfeeding
- Severe muscle problems or history of statin-induced muscle disease
Side Effects
Like all medicines, atorvastatin can cause side effects, although not everyone gets them.
Common side effects:
- Muscle aches or weakness
- Diarrhea or constipation
- Headache
- Indigestion or nausea
Serious side effects — seek medical attention immediately:
- Severe muscle pain, tenderness, or weakness (may indicate rhabdomyolysis)
- Yellowing of skin or eyes, dark urine (possible liver problems)
- Allergic reactions (rash, swelling, difficulty breathing)
Regular monitoring of liver function and cholesterol levels is usually recommended during treatment.
Pregnancy, Breastfeeding & Fertility
Atorvastatin should not be used during pregnancy or breastfeeding, as it may harm the baby.
There is no evidence that atorvastatin affects fertility in men or women.
Interactions With Other Medications
Some medicines can affect how atorvastatin works or increase the risk of side effects. Tell your doctor if you take:
- Certain antibiotics or antifungals (e.g., clarithromycin, itraconazole)
- Other cholesterol-lowering medicines (e.g., fibrates, niacin)
- Some heart medications (e.g., amiodarone, verapamil)
- Immunosuppressants (e.g., cyclosporine)
- Grapefruit or grapefruit juice — may increase the risk of side effects
Frequently Asked Questions
What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one — do not double up.
Can I drink alcohol while taking atorvastatin?
Moderate alcohol is generally safe, but excessive drinking may increase the risk of liver problems.
Can atorvastatin cause muscle problems?
Yes, muscle aches or weakness can occur. Contact your doctor if you experience severe or persistent muscle pain.
How long will I need to take atorvastatin?
Most people take atorvastatin long-term to manage cholesterol and reduce heart risk. Follow your doctor’s advice.
Can I take atorvastatin with other cholesterol medications?
Sometimes yes, under medical supervision. Your doctor will monitor for side effects and adjust doses as needed.
Medical Disclaimer: This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or changing any medication.
Last reviewed: June 2026
